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Vitamin B12 also upregulates brain-derived neurotrophic factor (BDNF) and increases nerve conduction velocity, which may reflect part of the regeneration process and brain plasticity [32]

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Intramuscular injections are often more effective than oral supplements for severe deficiencies or neurological symptoms, as they deliver B12 directly into your bloodstream and bypass absorption issues

It is also prohibited by the World Anti-Doping Agency, reflecting the absence of validated safety and efficacy data

In many experimental designs, it has also shown improvement in neural densities